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Virbac Effitix (Fipronil 6.1% + Permethrin 54.5%) Tick and Flea Spot On for Dogs
Most tick and flea spot-ons stop at killing what is already on your dog. Virbac Effitix goes further — it also repels what has not landed yet.
Virbac Effitix spot on for dogs is a dual-action ectoparasiticide that combines two active ingredients — Fipronil 6.1% w/v and Permethrin 54.5% w/v — to both kill existing infestations and actively repel new parasites before they can bite. Fipronil handles adult fleas, ticks, and lice through contact kill. Permethrin adds a powerful repellent layer that deters ticks, mosquitoes, and sandflies — keeping them off your dog's coat before they can attach, feed, or transmit disease.
This repellent activity against mosquitoes and sandflies is what makes Effitix stand out from plain Fipronil spot-ons. Mosquitoes transmit heartworm. Sandflies transmit Leishmaniasis. In India's tropical and high-mosquito-density urban environments, a spot-on that actively repels these vectors adds a meaningful layer of protection that Fipronil alone does not provide.
The formula is water-resistant — remaining effective after bathing, swimming, and sun exposure. Application uses Virbac's drop-stop pipette technology for precise, mess-free delivery. Available in 3 sizes for dogs from 4 to 40kg, each pack contains 2 pipettes.
(From Virbac Animal Health India Pvt. Ltd., Borivali East, Mumbai — the Indian arm of Virbac S.A., one of the world's leading dedicated veterinary pharmaceutical companies. Safe for dogs and puppies from 8 weeks of age)
Do not use on cats under any circumstances — Permethrin is highly toxic to cats, even at the concentrations used on dogs.
What Does Virbac Effitix Spot On Treat in Dogs?
Here is what Effitix fipronil permethrin spot on treats, prevents, and repels:
Tick control — kills adult ticks, including Rhipicephalus sanguineus (brown dog tick), Ixodes species, Dermacentor species, and Amblyomma species on contact, and provides residual protection for up to 4 weeks. Permethrin's repellent action also deters ticks before they attach — a meaningful advantage in heavy-tick environments where the volume of tick exposure is high
Flea treatment and prevention — Fipronil kills adult fleas within 6 hours of application and continues to protect for up to a month. Monthly use prevents flea reinfestation and manages flea allergy dermatitis in hypersensitive dogs
Lice control — kills both biting and chewing lice on contact, providing a full month of lice control with monthly application
Mite control — aids in the management of mite infestations, including those causing sarcoptic mange
Mosquito repellent — Permethrin actively repels mosquitoes and prevents blood feeding for up to 4 weeks. Mosquitoes are the primary vector for heartworm (Dirofilaria immitis) in India — repelling them reduces transmission risk in high-mosquito environments
Sandfly repellent — Permethrin repels sandflies, the vector for Leishmaniasis — a serious and potentially fatal parasitic disease increasingly documented in dogs in India, particularly in areas bordering endemic zones
Learn more about how to properly eradicate ticks & fleas from your dogs by reading our expert-approved blog: The Ultimate Remedy for Tick and Flea Removal for Dogs
How Do Fipronil and Permethrin Work Together?
Virbac Effitix works through two active ingredients with complementary but distinct mechanisms of action
Fipronil is a phenylpyrazole insecticide and acaricide that blocks GABA-gated chloride channels in the nervous systems of fleas, ticks, and lice, causing hyperexcitation, paralysis, and death on contact. After application, Fipronil spreads through the coat via the sebaceous glands and is continuously released onto the coat surface for up to a month
Permethrin is a synthetic pyrethroid that works both as an insecticide and as a repellent. As an insecticide, it disrupts voltage-gated sodium channels in insect nervous systems, causing paralysis and death. As a repellent, it creates an olfactory and contact deterrent barrier that prevents ticks, mosquitoes, and sandflies from landing or feeding on the treated coat
The combination of two active ingredients from different chemical classes also reduces the theoretical risk of resistance development — parasites would need to simultaneously overcome two different mechanisms to survive exposure
The water-resistant formulation binds to the coat and sebaceous gland reservoir and retains efficacy after bathing, swimming, and sun exposure — unlike some spot-ons that lose significant efficacy after water exposure
How Do You Apply Virbac Effitix Spot On to Your Dog?
Select the correct pipette size for your dog's bodyweight — see the dosage table below
Remove the pipette from the blister packaging and hold it upright
Tap the narrow tip to ensure all the solution is in the main body of the pipette
Snap or break the top along the scored line to open — the drop-stop design prevents overflow during opening
Part the fur along your dog's back until skin is visible
For dogs under 20kg, apply the entire contents across 2 spots along the spine
For dogs 20 to 40kg, apply across 2 to 4 spots along the spine from the shoulder to the base of the tail
Squeeze gently at each spot to empty — do not apply to a single point only
Do not rub in — allow to absorb and spread naturally
Keep your dog dry for 48 hours after application
Do not allow your dog to swim in water courses or ponds for 2 days after application — Permethrin is toxic to aquatic organisms